Biologically effective dose correlates with linear tumor volume changes after upfront single-fraction stereotactic radiosurgery for vestibular schwannomas

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Tissue changes after radiosurgery for vestibular schwannomas.

The specific effects of radiosurgery on brain tumor tissue are not well understood. We review several approaches that have been used to address this issue. Correlating the radiobiology of radiosurgery with the radioclinical outcome may help to understand these tissue changes. In vivo imaging investigations are usually performed with MRI, but the use of functional and metabolic imaging, such MR ...

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Linear accelerator stereotactic radiosurgery for vestibular schwannomas: a UK series.

AIMS To evaluate non-auditory toxicity and local control after linear accelerator stereotactic radiosurgery (SRS) for the treatment of vestibular schwannomas. MATERIALS AND METHODS The institutional policy was to use SRS for radiologically progressing vestibular schwannomas. Case notes and plans were retrospectively reviewed for all patients undergoing SRS for vestibular schwannomas between S...

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Radiosurgery for vestibular schwannomas.

BACKGROUND Radiosurgery has been established as an important alternative to microsurgery. We report our experience with radiosurgery for tumor control and the complications of unilateral vestibular schwannomas. METHODS We reviewed our early experience regarding clinical presentation, management and outcomes in 45 patients with acoustic schwannomas who underwent gamma knife stereotactic radios...

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Multisession stereotactic radiosurgery for vestibular schwannomas: single-institution experience with 383 cases.

BACKGROUND Single-session stereotactic radiosurgery (SRS) treatment of vestibular schwannomas results in excellent tumor control. It is not known whether functional outcomes can be improved by fractionating the treatment over multiple sessions. OBJECTIVE To examine tumor control and complication rates after multisession SRS. METHODS Three hundred eighty-three patients treated with SRS from ...

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Cochlea radiation dose correlates with hearing loss after stereotactic radiosurgery of vestibular schwannoma.

OBJECTIVE For multisession radiosurgery, no published data relate the volume and dose of cochlear irradiation to quantified risk of hearing loss. We conducted a retrospective, dosimetric study to evaluate the relationship between hearing loss after stereotactic radiosurgery (SRS) and the dose-volume of irradiated cochlea. METHODS Cochlear dose data were retrospectively collected on consecutiv...

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ژورنال

عنوان ژورنال: Neurosurgical Review

سال: 2021

ISSN: 0344-5607,1437-2320

DOI: 10.1007/s10143-021-01538-w